https://github.com/ActiveState/appdirs/commit/4463d5f7cef8dbe8a3455603a438f0f20028f428

--- appdirs-1.4.4/tox.ini.orig
+++ appdirs-1.4.4/tox.ini
@@ -2,4 +2,4 @@
 envlist = py26, py27, py32, py33, py34, py35, py36
 
 [testenv]
-commands = python setup.py test
+commands = {envpython} -m unittest discover